Source: www.ibtimes.com --- Saturday, April 06, 2013
Benchmark tests suggest the Samsung Galaxy S4 is the fastest smartphone. ...
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Source: www.ibtimes.com --- Saturday, April 06, 2013
Benchmark tests suggest the Samsung Galaxy S4 is the fastest smartphone. ...
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In mice, bits of proteins can treat condition resembling multiple sclerosis
By Nathan Seppa
Web edition: April 3, 2013
Tiny components of amyloid plaques, the notorious protein clumps found littering the brains of people with Alzheimer?s disease, might fight inflammation. Researchers report that several of these sticky protein fragments, or peptides, glom onto inflammatory compounds and reverse paralysis in mice that have a condition similar to multiple sclerosis. A fragment of tau protein, which shows up in other brain deposits in Alzheimer?s patients, has a similar effect.
When tested on blood taken from three MS patients, the tau peptide weeded out some inflammatory culprits there, too, researchers report in the April 3 Science Translational Medicine.
?This is a seriously good study. It opens up more questions than it answers,? says Jian-Guo Geng, a cell biologist at the University of Michigan in Ann Arbor who wasn?t part of the research team. ?But I don?t think we?re anywhere close to using these peptides for treatments.?
Amyloid is a broad term for clusters of protein in the brain, including those arising with the aid of misfolded versions of tau or another protein implicated in brain disease called a prion. Viewing amyloid-forming peptides as good guys runs against the scientific thinking, since amyloid plaques are a hallmark of Alzheimer?s disease. But study coauthor Lawrence Steinman, a neurologist at Stanford University, points out that the actual role of amyloid plaques in the disease is unclear. He suggests the tiny peptides holding the plaques together might have an alternative, useful role in the body.
Last year, Steinman and his team showed that injecting mice with amyloid improves symptoms in animals with the MS-like condition (SN: 9/22/2012, p. 14). Separately, Geng reported in 2012 that mice genetically engineered to make extra amyloid could fend off the MS-like disease, and that knocking out the amyloid-making capacity worsened symptoms in animals.
The new study goes a step further toward working out how amyloid fights disease in mice. In MS, inflammation is the enemy, damaging the fatty coatings on nerve sheaths in the central nervous system. A breakdown of that nerve insulation results in disordered nerve signaling and symptoms that can include weakness, loss of motor control, vision problems, loss of sensation and other problems.
Steinman and his colleagues identified several peptides, each only six amino acids in length, that seem to knock down inflammation when they twist to form sticky structures called fibrils. Steinman likens the peptide fibrils to sponges, because of their ability to bind to and contain compounds that trigger inflammation.
The researchers injected various peptides that can form amyloid in mice that had become disabled by the MS-like condition. Several of the peptides ? including fragments of heat shock proteins, tau protein and prion protein ? reversed the animals? paralysis during treatment. The effect later faded.
Blood samples from treated mice showed that heat shock and tau peptide fibrils had reduced levels of several proteins that cause inflammation, including interleukins 2 and 6. Compared with animals that received no fibril treatment, the animals? brain tissue had less inflammation.
When the scientists cultured human blood from MS patients with the tau fibril, the sticky peptide bound to dozens of compounds, including many molecules involved with inflammation.
The misfolded versions of tau, prions and amyloid protein can all form deposits in the brain, and it is the stickiness of fibrils that enables sheets of proteins to aggregate into these deposits, Steinman says. Those deposits have earned fibrils a nasty reputation.
?We have to keep an open mind,? he says. ?Most molecules are nuanced in function. In certain circumstances, they can cause harm or benefit.?
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We've been thinking a lot lately about the chefs, musicians, comedians, actors and others whose career frequently takes them out on the road, into more airplanes, restaurants and hotel bars than they can count. When they finally settle back in at home, what do they want to cook for themselves? We asked, and they just started telling us! Find out their answers in our series, Homecoming Meals.
We should have suspected that most of our Homecoming Meals participants would extoll the virtues of simple comfort food, but the consistency with which they've answered this way has delighted us. From Fabio's risotto to Jeni's unconventional ratatouille, simplicity totally rules. Today's edition is no exception: we caught up with "Top Chef" host, cookbook author and well-exposed food nerd, Padma Lakshmi.
Honestly it?s a simple bowl of lentils and rice. Or beans and rice. I?m very simple! Honestly most of my diet when I?m not working on ?Top Chef? is very simple, very plant based. So if it?s cold it will be a noodle soup and if it?s not cold it would probably be like beans and rice or lentils and rice. That?s really what I like.As for flavors, I always think even dessert should have a hint of salt in it. But in the case of the lentils and rice, it?s actually homey, comfort, savory porridge called Kitchedi. And I add cumin to that and green chilies for a little heat. I also add sometimes some chopped dried plums for a hint of tartness and sweetness. I think ?- not to plug my own book but -? the title of my own book actually sums up what I think about food, I like everything a little tangy, a little tart, a little hot and a little sweet. [Padma?s book is called Tangy, Tart, Hot and Sweet: A World of Recipes for Everyday.] I think that?s the perfect bite in your mouth because it hits all the different parts of your palate.
You catch that guys? We think she likes her Homecoming Meals to be simple. In honor of Padma's proclivity towards preparing lentil recipes, we've included some of our very favorites below.
Want to read more from HuffPost Taste? Follow us on Twitter, Facebook, Pinterest and Tumblr.
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/lentils-with-red-wine-and_n_1058526.html" target="_hplink">Lentils with Red Wine and Herbs recipe</a></strong>
<strong>Get the <a href="http://www.veggienumnum.com/2011/06/spicy-lentil-tart-w-pomegranate-mint/" target="_hplink">Spicy Lentil Tart with Pomegranate and Mint recipe from Veggie Num Num</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/lentil-cilantro-and-chil_n_1057584.html" target="_hplink">Lentil, Cilantro and Chili Salad with Warm Cauliflower Florets recipe</a></strong>
<strong>Get the <a href="http://inspiringtheeveryday.com/2011/12/30/braised-french-lentils-vegetables/" target="_hplink">Braised French Lentils and Vegetables recipe from Inspiring the Everyday</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/french-lentils-with-roast_n_1061280.html" target="_hplink">French Lentils with Roasted Roots, Caramelized Onions and Thyme recipe</a></strong>
<strong>Get the <a href="http://www.crumblycookie.net/2012/04/23/lentil-tacos/" target="_hplink">Lentil Tacos recipe from The Way the Cookie Crumbles</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/veggie-burgers-with-pomeg_n_1061058.html" target="_hplink">Lentil Veggie Burgers with Pomegranate Ketchup recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/green-lentil-curry_n_1058427.html" target="_hplink">Green-Lentil Curry recipe</a></strong>
<strong>Get the <a href="http://www.indiansimmer.com/2011/08/art-of-making-crisp-dosa.html" target="_hplink">Dosa recipe from Indian Simmer</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/lentil-soup-with-kielbasa_n_1056848.html" target="_hplink">Lentil Soup with Kielbasa and Kale recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/bulgur--lentils_n_1062560.html" target="_hplink">Bulgur and Lentils recipe</a></strong>
<strong>Get the <a href="http://www.kalynskitchen.com/2012/01/recipe-for-vegan-lentil-chili-with.html" target="_hplink">Vegan Lentil Chili with Roasted Red Peppers, Olives and Green Onion recipe from Kalyn's Kitchen</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/12/15/veggie-balls_n_1151673.html" target="_hplink">Lentil Veggie Balls recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/grilled-green-bean-salad-_n_1058446.html" target="_hplink">Grilled Green Bean Salad with Lentil Vinaigrette recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/garlicky-lentil-soup-with_n_1057206.html" target="_hplink">Garlicky Lentil Soup with Vinegar and Olive Oil recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/stuffed-vegetables-with-l_n_1057506.html" target="_hplink">Stuffed Vegetables with Lentils, Rice, Pine Nuts and Parsley recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2012/03/06/birbal-kee-khitcheree_n_1324382.html" target="_hplink">Birbal Kee Khitcheree recipe</a></strong>
<strong>Get the <a href="http://tastyeasyhealthygreen.com/?p=1327" target="_hplink">Farro and Lentils with Sauteed Kale and Trumpet Mushrooms recipe from Tasty Easy Healthy Green</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/green-lentil-salad-with-c_n_1059864.html" target="_hplink">Green Lentil Salad with Cucumber and Cumin and Lemon Vinaigrette recipe</a></strong>
<strong>Get the <a href="http://bevcooks.com/2012/01/beef-and-lentil-curry/" target="_hplink">Beef and Lentil Curry recipe from Bev Cooks</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/very-green-lentil-soup_n_1062559.html" target="_hplink">Very Green Lentil Soup recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/spiced-eggplant-lentil-sa_n_1062159.html" target="_hplink">Spiced Eggplant-Lentil Salad with Mango recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/lentil-coconut-soup-with-_n_1057264.html" target="_hplink">Lentil Coconut Soup with Lentil Apple Salad recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/black-lentil-and-bell-pep_n_1061450.html" target="_hplink">Black Lentil and Bell Pepper with Mint Salad recipe</a></strong>
<strong>Get the <a href="http://www.keepitsimplefoods.com/vegetarian/meatless-monday-meat-loaf/" target="_hplink">Lentil Loaf recipe from Keep It Simple Foods</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/squash-chickpea--red-le_n_1049445.html" target="_hplink">Squash, Chickpea and Red Lentil Stew recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/warm-lentil-salad-with-sa_n_1062568.html" target="_hplink">Warm Lentil Salad with Sausage and Apple recipe</a></strong>
<strong>Get the<a href="http://www.huffingtonpost.com/2011/10/27/dilled-lentil-soup-with-m_n_1056852.html" target="_hplink"> Dilled Lentil Soup with Mushrooms and Tomatoes recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/rice--lentil-salad_n_1062030.html" target="_hplink">Rice and Lentil Salad recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/lentil-burgers_n_1062535.html" target="_hplink">Lentil Burgers recipe</a></strong>
<strong>Get the <a href="http://www.huffingtonpost.com/2011/10/27/lentil-and-sun-dried-pest_n_1057463.html" target="_hplink">Lentil and Sun-dried Pesto Salad with Roasted Peppers recipe</a></strong>
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Source: http://www.huffingtonpost.com/2013/04/03/homecoming-meals-padma-lakshmi_n_3001118.html
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The Hybrid Memory Cube Consortium has been almost too patient in developing a standard for for its eponymous technology -- efforts began 17 months ago -- but it at last has more than good intentions to show for its work. Its just-published HMC Specification 1.0 lets companies build platforms and RAM with 2GB, 4GB and 8GB chips incorporating the stacked, power-efficient technology, all without compatibility jitters from other supporters. The completed spec is a scorcher when living up to its full potential, too. With eight links, a memory cube can reach a peak 320GB/s (yes, that's gigabytes) of aggregate bandwidth -- more than a hair faster than the 11GB/s we often get from existing DDR3 memory.
The Consortium is teasing us with more. Although we'll have to wait until the second half of the year before HMC 1.0 products appear in earnest, the Consortium already has a next-gen blueprint due in early 2014 that should nearly double individual data link speeds (from 15Gbps to 28Gbps). While we'd like to see the group walk the walk with real products before it talks more talk, there's still a chance that some memory performance bottlenecks could vanish for a good, long while.
Filed under: Storage, Samsung, Microsoft, HP
Via: Computerworld
Source: Hybrid Memory Cube Consortium
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/ER-HxhiKSHY/
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North Korea pressures South by halting entry to industrial zone
PAJU, South Korea (Reuters) - North Korea closed access to a joint factory zone with South Korea on Wednesday, officials said, putting at risk $2 billion a year in trade that is vital for an impoverished state with a huge army, nuclear ambitions and a hungry population. The move marked an escalation in North Korea's months-long standoff with South Korea and its ally Washington. On Tuesday, Pyongyang said it would restart a mothballed nuclear reactor, drawing criticism from the international community, including China, its major benefactor and diplomatic friend.
Hostilities flare along Israeli-Gaza border
JERUSALEM (Reuters) - Israel pressed Hamas on Wednesday to rein in rocket-firing militants in the Gaza Strip after the most serious outbreak of cross-border hostilities since the ceasefire that ended an eight-day war in November. The flare-up, sparked by anger in Gaza over the death from cancer of a Palestinian held by Israel, included Israel's first air strike on the Hamas-run coastal enclave since the truce.
Afghan Taliban kill 44 in suicide attack on courtroom
HERAT, Afghanistan (Reuters) - Nine Taliban suicide bombers killed themselves and 44 others on Wednesday in an attack on a courtroom in western Afghanistan where 10 of their comrades were on trial, a local official said. Causing the biggest death toll in a single attack since 2011, the militants, strapped with explosives, stormed the governor's compound in the capital of Farah province, bordering Iran, where the trial was taking place.
Analysis: Mali insurgency endangers French pull-out plan
PARIS (Reuters) - France wants to cut its forces in Mali sharply by the year-end and is urging its ex-colony to hold elections in July, but an Islamist insurgency is threatening that timetable. Many people in northern Mali who lived under the rebels' brutal form of Islamic law last year are apprehensive about French plans to leave just 1,000 of the current 4,000 troops in the country by December, with U.N. peacekeepers filling the gap.
Pope stresses "fundamental" value of women in Church
ROME (Reuters) - Pope Francis stressed the "fundamental" importance of women in the Roman Catholic Church on Wednesday, a message hailed as a significant shift from the position of his predecessor Benedict. Supporters of liberal reform of the Church have called on it to give a greater voice to women and recognize their importance to the largest religious denomination in the world, and some groups call for women to be ordained as priests.
Libya investigating Zueitina oil pipeline blast
NEAR ADJABIYAH, Libya (Reuters) - Libya is investigating the cause of an explosion late on Tuesday on oil and condensate pipelines to the eastern port of Zueitina, the National Oil Corporation (NOC) said. The blast occurred at 10 p.m. local time on a section of the pipeline linking Field 103, which is operated by Zueitina Oil company, to the export terminal, the state energy company said in a statement on its website.
U.S. sends missile defenses to Guam over North Korea threat
WASHINGTON (Reuters) - The Pentagon said on Wednesday it was sending an advanced ballistic missile defense system to Guam in the coming weeks, as U.S. Defense Secretary Chuck Hagel cited a "real and clear" danger from North Korea. North Korea has singled out U.S. military bases in Guam, a U.S. territory in the Pacific, and Hawaii among its potential targets in threats in recent weeks that have put the Korean peninsula on edge and triggered a change in the U.S. defense posture and missile defense planning.
Portuguese government defeats no confidence motion
LISBON (Reuters) - Portugal's government defeated a no confidence motion on Wednesday, yet the move united all the opposition in parliament against austerity policies and rattled the stock market. The vote was largely symbolic as the ruling centre-right coalition holds a comfortable majority, but Prime Minister Pedro Passos Coelho said the motion gave the impression of political instability just when Lisbon needs investor confidence to regain full access to debt markets.
Western envoys to attend ICC-indictee Kenyatta's inauguration
NAIROBI (Reuters) - The United States and several other European nations are expecting to send ambassadors to attend the swearing in next week of Uhuru Kenyatta, Kenya's president-elect who is indicted for crimes against humanity at The Hague. Western diplomats said this level of attendance was in line with their policy of having only "essential contacts" with indictees of the International Criminal Court. A European Union official also said EU envoys were seeking to meet Kenyatta.
Syrian jet flies into Lebanon, fires missile
ARSAL, Lebanon (Reuters) - A Syrian jet flew 20 km (12 miles) into Lebanon and fired a missile into a field on the outskirts of the border town of Arsal on Wednesday but caused no casualties, witnesses said. Lebanon has maintained a policy of "dissociation" from Syria's two-year-old conflict. But many Lebanese officials feel their country is increasingly at risk of being dragged into the civil war, which the United Nations says has killed 70,000 people.
Source: http://news.yahoo.com/ca-news-summary-000458404.html
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Dallas Stars forward forward Jaromir Jagr (68) waves to the fans as he received a standing ovation during the third period of an NHL hockey game against the Minnesota Wild Friday, March 29, 2013, in Dallas, Texas. Jagr got his 1000th assist during the game. (AP Photo/Sharon Ellman)
Dallas Stars forward forward Jaromir Jagr (68) waves to the fans as he received a standing ovation during the third period of an NHL hockey game against the Minnesota Wild Friday, March 29, 2013, in Dallas, Texas. Jagr got his 1000th assist during the game. (AP Photo/Sharon Ellman)
Dallas Stars forward forward Jaromir Jagr (68) skates during the third period of an NHL hockey game against the Minnesota Wild Friday, March 29, 2013, in Dallas, Texas. Jagr got his 1000th assist during the game. (AP Photo/Sharon Ellman)
BOSTON (AP) ? The Boston Bruins have acquired Jaromir Jagr from the Dallas Stars in an attempt to improve their shaky offense.
The 10th leading goal scorer in NHL history, who leads the Stars in points this season, Jagr was traded Tuesday for two prospects, forwards Lane MacDermid and Cody Payne, and a conditional second-round pick in this year's draft, the Stars announced.
The deal came five days after the Bruins thought they obtained forward Jarome Iginla from the Calgary Flames, only to learn Iginla had been traded to the Pittsburgh Penguins.
In his first season with the Stars, the 41-year-old Jagr has 14 goals and 26 points. Brad Marchand leads the Bruins with 14 goals and Patrice Bergeron is first with 31 points. Jagr has 679 career goals.
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By Andy Bruce
LONDON (Reuters) - Evaporating hopes for an economic recovery and last month's botched bailout of Cyprus persuaded analysts to chop their outlook again for the euro over the coming months, a Reuters poll showed.
Although the median expectation of more than 60 analysts surveyed over the last few days shows the euro trading around its current levels near $1.28 over the next few months, further out, the poll shows the currency weakening to around $1.25.
Overall, forecasts for the euro were about 2 cents weaker compared with last month's poll, which also reflected its roughly 6 percent depreciation against the dollar since the start of February.
The poor state of the euro zone economy was the chief reason why the euro is expected to weaken further, with surveys on Tuesday showing a worsening manufacturing slump in the currency bloc.
The median outlook for the euro was the weakest since September last year, when European financial markets were in turmoil as speculation grew that Spain would soon need a banking sector bailout, which it eventually got in December.
"We expect euro zone fundamentals to deteriorate further. This, combined with outflow pressures, should keep the euro's downward trend intact," said Camilla Sutton, chief currency strategist at Scotiabank in Toronto.
Asked which currencies investors were most likely to buy at the expense of the euro following the Cyprus bailout, 22 out of the 26 who answered said the U.S. dollar, with seven responses each for sterling and the Australian dollar.
"If the euro comes under further stress, we expect the growth-linked currencies like the Australian and Canadian dollars to benefit instead," said Emmanuel Ng, currency strategist at OCBC Bank in Singapore.
EURO BEARS OUT IN FORCE
Cyprus struck a 10-billion euro bailout deal with the European Union and International Monetary Fund last week, designed to untwine it from a failed banking sector that has long dominated its economy.
While tiny in economic terms, the chaotic bailout deal highlighted the political discord that has left Europe's economy rudderless, with the latest data showing signs of further deterioration rather than recovery.
The euro's recent decline versus the dollar reflects these poor economic fundamentals far more so than ebullient European stock markets. The FTSEurofirst 300 index has rallied more than 6 percent since the start of the year.
The poll showed the euro declining to $1.27 in six months, and $1.25 a year from now.
Bearishness about the euro's prospects among respondents was palpable, matching data from the Commodity Futures Trading Commission that showed traders increased their short bets against the euro through March.
Out of 58 contributors who took part in both the April and March foreign exchange polls, slightly more than half, 31, cut their 12-month outlook for the euro.
Fewer than a third of analysts expect the euro to be stronger in 12 months than its current level near $1.28.
Against sterling, analysts expect the euro to trade near 85 pence over the next year.
(Analysis by Somya Gupta and Namrata Anchan; Polling by Somya Gupta and Ashrith Doddi; Editing by Susan Fenton)
Source: http://news.yahoo.com/poll-euro-outlook-cut-again-botched-cyprus-bailout-170533274--business.html
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